coRNAi (version 1.22.0)

LS main: main effect estimation

Description

for rlmmain the main effects are estimated using rlm function from MASS package, with lmmain the OLS is used.

Usage

rlmmain(df,per=NULL)
lmmain(df,per=NULL)

Arguments

df

df dataframe created by function cellHTS2df

per

string argument for which factor the analysis should be done separately, eg. replicate or batch

Value

lm,rlm

See Also

rlm,lm

Examples

data(screen1_raw)
df = cellHTS2df(screen1_raw,neutral="Fluc")
df = weightDf(df,exclude=c("controlP1","controlP2","controlN1","controlN2","controlP1N1","double"))
mains = rlmmain(df)
hist(coef(mains))